Pre-Hollmann Lab

The publications below represent research conducted during my graduate and postdoctoral training. Together, these projects shaped my understanding of molecular mechanisms and helped develop the interdisciplinary approach that now defines the Hollmann Lab, integrating structural biology, biochemistry, and cellular biology to understand how RNA–protein interactions drive biological function:

Published at bioRxiv and under revision:

“Structural Basis for Dimeric Genome Selection by HIV-1” – Nele Merret Hollmann, Siarhei Kharytonchyk, Angela Buchanan, Caela Phillips, Amir Ledbetter, Fairine Ahmed, Anna Adelstein, Kaylee Barry, Samuel A. Geleta, Cleo Burnett, Alice Telesnitsky, Barbie K. Ganser-Pornillos, Owen Pornillos, Michael F. Summers. doi: https://doi.org/10.64898/2026.06.17.732839

Published at JMB:

“Optimized Preparation of Segmentally Labeled RNAs for NMR Structure Determination” – Brian D Grossman, Bethel G Beyene, Bersabel Tekle, William Sakowicz, Xinjie Ji, Joshua Miguele Camacho, Nandini Vaishnav, Amina Ahmed, Naman Bhandari, Kush Desai, Josiah Hardy, Nele M Hollmann, Jan Marchant, Michael F Summers. JMB, 437.10.169073, (2025), https://doi.org/10.1016/j.jmb.2025.169073

Published at PNAS:

“Role of RNA structural plasticity in modulating HIV-1 genome packaging and translation” – Saif Yasin, Sydney L Lesko, Siarhei Kharytonchyk, Joshua D Brown, Issac Chaudry, Samuel A Geleta, Ndeh F Tadzong, Mei Y Zheng, Heer B Patel, Gabriel Kengni, Emma Neubert, Jeanelle Mae C Quiambao, Ghazal Becker, Frances Grace Ghinger, Sreeyasha Thapa, A’Lyssa Williams, Michelle H Radov, Kellie X Boehlert, Nele M Hollmann, Karndeep Singh, James W Bruce, Jan Marchant, Alice Telesnitsky, Nathan M Sherer, Michael F Summers. PNAs, 121.33.e2407400121, (2024), https://doi.org/10.1073/pnas.2407400121

Published at eLife:

“The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase” – Valentin Bohl, Nele Merret Hollmann, Tobias Melzer, Panagiotis Katikaridis, Lena Meins, Bernd Simon, Dirk Flemming, Irmgard Sinning, Janosch Hennig & Axel Mogk. eLife 12, RP92746 (2024), https://doi.org/10.7554/eLife.92746.2

Published at Nature Communications:

“Crystal structure of a highly conserved enteroviral 5’ cloverleaf RNA replication element” – Naba K. Das, Nele Merret Hollmann, Jeff Vogt, Spiridon E. Sevdalis, Hasan A. Banna, Manju Ojha & Deepak Koirala. Nat Commun 14, 1955 (2023), https://doi.org/10.1038/s41467-023-37658-8

Published at Nucleic Acids Research:

“Upstream of N-Ras acts as a ribonucleoprotein assembly platform during translation regulation” – Nele Merret Hollmann,Pravin Kumar Ankush Jagtap, Johanna-Barbara Linse, Philip Ullmann, Marco Payr, Brice Murciano, Bernd Simon, Jochen S. Hub & Janosch Hennig. Volume 51, Issue 4, 28 February 2023, Pages 1895-1913, https://doi.org/10.1093/nar/gkac1277

Published at Cell Reports:

“Pseudo-RNA binding domains mediate RNA structure specificity in Upstream of N-Ras” - Nele Merret Hollmann, Pravin Kumar Ankush Jagtap, Pawel Masiewicz, Tanit Guitart, Bernd Simon, Jan Provaznik, Frank Stein, Per Haberkant, Lara Jayne Sweetapple, Laura Villacorte, Dylan Mooijman, Vladimir Benes, Mikhail M. Savitski, Fátima Gebauer & Janosch Hennig. Cell Rep. 2020 Jul 21;32(3):107930. doi:10.1016/j.celrep.2020.107930.

Published at Nature Communications:

“Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions” - Ignacio L. Ibarra, Nele Merret Hollmann, Bernd Klaus, Sandra Augsten, Britta Velten, Janosch Hennig & Judith B. Zaugg. Nat Commun 11, 124 2020, https://doi.org/10.1038/s41467-019-13888-7

Published at Nucleic Acids Research:

“Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1 and 2 of Drosophila Maleless”- Pravin Kumar Ankush Jagtap, Marisa Müller, Pawel Masiewicz, Sören von Bülow, Nele Merret Hollmann, Bernd Simon, Andreas W. Thomae, Peter B Becker & Janosch Hennig. Volume 47, Issue 8, 07 May (2019), Pages 4319–4333,https://doi.org/10.1093/nar/gkz125